The upcoming NFL Week 3 game features the Buffalo Bills hosting the Miami Dolphins at Highmark Stadium on September 18th at 8:15 p.m. The Bills, with a 2-0 record, are favorites to win, with odds favoring them by 12.5 points and a high confidence level of 75.8% according to ESPN predictions. The Dolphins, currently 0-2, are aiming to break a five-game losing streak against the Bills, who have dominated their recent matchups, including a 13-1 record against Miami over the last 14 games. Experts predict a strong performance from Buffalo, with some estimating they could win by as much as 30 points, and the game total set at 49.5 points. The Bills are considered highly likely to secure the victory, with betting odds reflecting an 80% chance of winning. Meanwhile, Dolphins coach Mike McDaniel remains optimistic despite the team's struggles, emphasizing the short week as a chance to focus solely on the upcoming game. Miami has conceded 66 points in their first two games, losing to Indianapolis and New England, but showed improvement in Week 2. McDaniel is under pressure with the Dolphins' recent poor performance and the threat of an 0-3 start, which historically makes playoff qualification nearly impossible. Despite the adversity, McDaniel maintains a positive outlook, focusing on the importance of team trust and effort. The game will be available to watch on Prime Video, with various streaming options and radio broadcasts for fans. The matchup is critical for Miami's season, as a loss would deepen their struggles and diminish playoff hopes, while Buffalo aims to continue their winning streak and maintain dominance in the AFC East.