West Ham United hosts Brentford at the London Stadium in a Premier League match on October 20, 2025, kicking off at 8:00 p.m. local time. West Ham, sitting 19th with 4 points, is seeking their first win under new manager Nuno Espírito Santo, who has overseen two away games resulting in a draw and a loss. Brentford, in 16th place with 7 points, has recently defeated Manchester United 3-1 but lost to Manchester City 1-0. The match will be streamed via FuboTV and NBC Sports App, with kickoff at 3:00 p.m. ET in the US. Team news indicates minimal changes for West Ham, with goalkeeper Alphonse Areola likely to start despite recent goals conceded. Defenders El Hadji Malick Diouf, Konstantinos Mavropanos, and Max Kilman are expected to continue, with Kyle Walker-Peters possibly replacing Aaron Wan-Bissaka. Midfielders Soungoutou Magassa and Mateus Fernandes are set to operate as double pivots, with Lucas Paqueta maintaining his role as No.10. Up front, Jarrod Bowen, Crysencio Summerville, and potentially Callum Wilson are in line to start. Brentford faces injuries with Antoni Milambo out long-term due to an ACL injury, and others like Edmond-Paris Maghoma, Gustavo Nunes Fernandes Gomes, Yegor Yarmoliuk, and Aaron Hickey dealing with minor knocks or recovery. Predicted starting XI for Brentford includes goalkeeper Kelleher, defenders Collins, Van den Berg, Hickey, and midfielders Henderson, Yarmoliuk, with attackers Schade and Thiago. Historical stats show West Ham has only one win in eight Premier League matches against Brentford, with the last encounter ending in a 1-1 draw in September 2024. Brentford has a strong record against West Ham, with six wins in 11 matches. Both teams are struggling at home and away this season, with West Ham losing all three home games and Brentford all three away games. Key statistics highlight Brentford's high number of long throw-ins and West Ham's low possession percentage. The Premier League fixture schedule includes other matches this week, with notable games such as Nottingham Forest vs Chelsea and Liverpool vs Manchester United. The match is part of the ongoing season where both teams aim to improve their standings amid recent form struggles.